MLAB 2201 - Clinical Immunology

2 sem hrs cr (15 lecture hours/30 laboratory hours)

Basic principles of the immune system structure and function in health and disease.  Topic include principles of a natural and acquired immunity, hypersensitivity, autoimmunity, immunodeficiency, transplant and tumor immunology, immunological techniques and flow cytometry. Prerequisite: Program Restriction—Enrollment limited to students admitted to the MLT program

Transfer (UT) or Non-Transfer Course (UN): UN

Upon completion of this course, students will be able to…

• define natural and acquired immunity and to list and describe both the cells and other components of the immune system.
• differentiate cell-mediated from antibody-mediated immunity and discuss the features of antigens that illicit an immune response.
• describe the complement system and its importance in the immune response.
• describe immunoglobulins with emphasis on their classes, structures, serum concentrations, ability to cross the placenta, and complement fixation.
• discuss and describe basic immunoassay principles and procedures.
• describe autoimmune disorders, including both tolerance and proposed mechanisms, as well as the major clinical and laboratory features that are seen.
• describe immunodeficiency disorders and differentiate the laboratory findings of B-cell and T-cell immunodeficiencies.
• list and define the types of hypersensitivity and discuss the immunologic mechanisms unique to each.
• evaluate the suitability of clinical specimens for immunological testing.
• evaluate laboratory test outcomes and correlate with disease or immune system status.
• exhibit professionalism, self-motivation, and responsibility.